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Collagen and Vitamin C Supplements: A Dynamic Duo for Arthritis, Tendonopathy, and Fracture Healing in the Athletic and Active Aging Community

In the world of sports medicine, optimizing recovery is crucial for both the broad population of athletes and active aging individuals dealing with arthritis, tendonopathy, and fractures. Emerging research, such as the scoping review published in Nutrients, sheds light on the promising roles of collagen and vitamin C supplements in promoting healing and managing these conditions [1]. Let’s explore the evidence supporting their use and how they can be be a part of a holistic pursuit of optimal musculoskeletal health for an athletic population.

Collagen and Arthritis Management:

Arthritis, characterized by joint inflammation, can significantly impact athletes and active aging individuals alike. Collagen, a vital component of connective tissues, has shown promise in managing arthritis symptoms. Studies indicate that collagen supplementation may reduce joint pain and improve functionality in individuals with osteoarthritis [2].

Tendonopathy and Collagen Supplementation:

Tendonopathy, often experienced as pain and dysfunction in tendons, is a common challenge for athletes. Collagen supplements have demonstrated potential in supporting tendon health. Research suggests that collagen supplementation may enhance collagen synthesis in tendons, promoting structural integrity and potentially reducing the risk of injury [3]. Notably, a scoping review on the efficacy of vitamin C supplementation in tendinopathy treatment highlights its potential therapeutic benefits by increasing collagen synthesis [1].

Vitamin C and Fracture Healing:

Vitamin C is a key player in collagen synthesis and has been linked to bone health. In the context of fracture healing, adequate vitamin C levels are crucial. A study emphasizes the importance of vitamin C for fracture healing, indicating that deficiency may impede the process [4].

Combined Approach for Comprehensive Healing:

The synergy between collagen and vitamin C is evident in their combined impact on musculoskeletal health. Research suggests that combining collagen and vitamin C supplementation may enhance collagen synthesis and accelerate the healing process [5].


As athletes and active aging individuals strive for peak performance and well-being, the use of collagen and vitamin C supplements emerges as a promising strategy in sports medicine. From managing arthritis symptoms to supporting tendon health and accelerating fracture healing, the evidence suggests a positive impact. However, individual responses may vary, and consultation with a healthcare professional is advisable. The dynamic duo of collagen and vitamin C, supported by recent research findings, opens new avenues for comprehensive musculoskeletal care, empowering a diverse population of athletes to pursue their fitness and health goals with confidence.


[1] Effect of Vitamin C on Tendinopathy Recovery: A Scoping Review. Nutrients. 2022 Jul; 14(13): 2663. Published online 2022 Jun 27. doi: 10.3390/nu14132663. PMCID: PMC9267994. PMID: 35807843.

[2] Porfirio, B., Guerra, F., Mari, D., Caccavo, D., & Lupoli, G. A. (2018). The Effects of Collagen Peptides on Joint Pain in Osteoarthritis and Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled Study. Journal of Medicinal Food, 21(5), 511–520.

[3] Shaw, G., Lee-Barthel, A., Ross, M. L., Wang, B., & Baar, K. (2017). Vitamin C–Enriched Gelatin Supplementation Before Intermittent Activity Augments Collagen Synthesis. The American Journal of Clinical Nutrition, 105(1), 136–143.

[4] Traxler, M., Zwerina, J., Tzankov, A., Meier, J. K., & Mueller, L. A. (2019). Vitamin C Deficiency in a Population of Young Patients with Severe Fractures. International Journal of Environmental Research and Public Health, 16(19), 3657.

[5] Moskowitz, R. W. (2000). Role of Collagen Hydrolysate in Bone and Joint Disease. Seminars in Arthritis and Rheumatism, 30(2), 87–99.